The Progression of End-Stage Renal Failure

What is End-stage Renal Failure (ESRF)? ESRF or uremia refers to the advanced stage of kidney disease. Uremia describes a series of clinical symptoms of advanced kidney disease, when one’s medical condition progresses to End-stage Renal Failure, he or she almost loses the kidney function completely. Uremia appears as a result of the Renal Failure.

The early stage of ESRF or uremia is called Chronic Renal Failure. The diving line of different stages of Renal Failure is based on the GFR (glomerular filtration rate). When one’s GFR is less than 15%, the medical definition is called ESRF. While one’s GFR is less than 30% but over 15%, it is called Chronic Renal Failure (CRF). It can be said that CRF is the prelude of ESRF. By experiences, the reduction of GFR from 30% to 15%, sometimes, is just a momentary matter.
Therefore, once the disease condition progresses to Chronic Renal Failure, the patients should be extremely careful to the treatment received. Otherwise the illness condition can progress to End-stage Renal Failure promptly even before you know it.

By clinical experience, the reduction of GFR can happen within several days or months. That’s why Renal Failure is regarded as the prelude of advanced kidney disease.

I sincerely recommend you to take timely treatment as early as possible. In the early stage of CKD (Chronic Kidney Disease), for example, CKD stage 2, there still stands a chance to reverse it if take immediate as well as correct treatment. If failed, the Renal Failure is awaiting you on the road ahead.