Can Patients with FSGS Drink Alcohol

For many people, drinking alcohol is a pleasure in their life. However, for the patients with FSGS, they are generally not recommended to drink alcohol for it may cause the following impacts on them.

1. For the patients on medications, alcohol can complicate how medications work. They should check with the doctor about drinking alcohol while on medication.

2. Drinking can increase the chance of developing blood pressure. It can accelerate the renal function deterioration rate. If the patients have high blood pressure it can make it harder to keep the blood pressure controlled.

3. Large amount of alcohol consumption can cause much damage to heart, thus elevating the risks of developing heart failure which is one of major death causes of FSGS.

4. Alcohol can impair kidney cells directly and increase the risk of needing dialysis for the patients with FSGS.

5. As many patients with FSGS suffer from hyperlipidaemia, the carbohydrate load in alcohol can deteriorate this condition significantly.

6. Drinking alcohol can lower the body's immune system, which makes it easier for the relapse of the disease.

In terms of the impacts on body, the patients with FSGS are not recommended to drink alcohol. If they do this, they should get OK from their doctors firstly.

Apart from abandoning alcohol, the following diet tips also work well in slowing the disease progress.

Low calorie beverages

The beverages plays a role in management of the kidney disease. The patients should limit the fluid intake to prevent retention of fluid so as to relieve swelling. They can drink water, low-fat milk and clear soft drinks and restrict cola soft drinks are rich in phosphoric acid which can elevate phosphorus in blood.

Lean meats

If the patients with FSGS develop renal insufficiency, they should eat 0.6g of protein per kg of body weight each day. As poultry and lean meats are loaded in proteins, the patients should limit its intake to avoid putting additional strain on the kidneys.

Also, the patients should reduce the intake of foods high in phosphorus, sodium.
As the patients' conditions varies from case to case, the patients with FSGS should discuss with their doctor or dietitian before making a kidney diet plan.

What Are the Common Complications of FSGS

FSGS is commonly seen in both children and adults. It refers to a disorder, in which the filters (glomeruli) in kidneys are inflamed. For long-term use of hormone and cytotoxic agents and kidney damage, the patients with FSGS usually experience a series of complications, as follows:

Infection

Infection is commonly seen in FSGS. Proteins are important nutrients and antibodies in body. For massive protein leakage in FSGS, the levels of IgG and complement proteins decrease. As a result, the immunity weakens thus resulting in high risk of developing infections which can cause the relapse of the disease and even threaten the patients’ life.

Malnutrition

Proteins are the main nutrients and they are the major sources of energy for systemic organs and tissues. The patients with FSGS are very susceptible to the experience malnutrition for protein leakages. If the body can not get sufficient nutrients supply, it can cause amyotrophy and slow down the skeletal development. That is why the children with FSGS are shorter than the healthy children of the same age.

Anemia

Proteins are responsible for carrying iron to every part in body. Due to protein leakages, there is no sufficient iron for transporting iron thus resulting in anemia.

High blood pressure

High blood pressure is a common complication of FSGS. It is mainly attributable to two causes. Firstly, the glomeruli can not discharge excess fluid from body thus resulting in increased blood volume. Secondly, for renal ischemia and anoxia, more angiotensin is produced thus contracting blood vessels.

Osteoporosis

Osteoporosis is commonly seen in FSGS for vitamin deficiency. Vitamin D binds to proteins in blood. Some vitamin D will leak into urine along with proteins.

How to Lower High Creatinine Level in FSGS in Natural Ways

FSGS can be seen in both children and adults. It is a major cause of ESRD for adults. As the glomeruli (filters) in kidneys are sclerotic partially, the kidneys are not capable of functioning adequately, resulting in accumulation of metabolic wastes in blood. As a result, the creatinine level will be higher than normal. So, how to lower high creatinine level in FSGS effectively?

Keep a healthy diet

The creatinine is the end products of creatine in muscle. Too much consumption of meat can produce more creatinine in blood. Therefore, the patients should limit their daily intake of meat strictly.

Avoid strenuous exercise

Strenuous exercise can accelerate the metabolism of creatine in muscle thus producing more creatine in body. This will inevitably put much strain on kidneys when it is excreted by kidneys. So the patients with FSGS should avoid strenuous exercise and take part in aerobic exercise jogging, bicycling, swimming etc.

Micro-Chinese Medicine Osmotherapy

Micro-Chinese Medicine Osmotherapy can remove creatinine and other metabolic wastes in blood thus lowering high creatinine in FSGS. Meanwhile, it can restore the impaired kidney tissues and recover the excretory function of the kidneys.

① Micro-Chinese Medicine Osmotherapy is an external therapy. When it is performed on body, it can open up pores. A part of toxins in body can be passed out of body through pores.

② The effective medicines can dilate systemic blood vessels and improve microcirculation in kidneys. Therefore, it can boost the excretion of metabolic wastes thus lowering high creatinine level.

③ Micro-Chinese medicine can activate the reproduction of DNA of the impaired renal functional cells, thus restoring the injured kidneys.

When the kidneys are restored very well, their excretory function will improve significantly. As a result, the high creatinine will decline gradually.
Stem Cell Therapy can treat FSGS from its underlying cause. Therefore, the patients can have a complete recovery without relapse.

FSGS with GFR 17

FSGS is a hard disease to treat and the renal function deteriorates at a very fast speed. How to treat it with GFR 17?

GFR 17 means that FSGS is in stage 4 Chronic Kidney Disease. Without timely control, dialysis or renal transplantation will be required soon. Then, is there alternative therapy to FSGS along with GFR 17?

FSGS is an immune-mediated disorder, in which the immune system attacks the healthy kidney tissues and cells mistakenly. Immune system is a strong protective system in body and it can defeat the foreign pathological substances when they invade body

In FSGS, the foreign bacteria such as upper respiratory tract infection activates the immune system to defeat the infection bacteria. However, for immune dysregulation, the immune system fails to defeat the bacteria or other pathological substances. As a result, these foreign substances may combine with the antibodies to form immune complexes in blood, afterwards, flow into kidneys. To clear up the immune complexes, the body activates an inflammatory response to remove them, thus leading to inflammatory response in kidney. The inflammatory response may attract more and more inflammatory mediator to aggravate the immune injury in kidneys. As a result, the kidney tissues and cells will become sclerotic and finally necrotic finally.

Immunotherapy is the latest therapy for FSGS. The main types of immunotherapy now being used to treat FSGS are as follows:

Monoclonal antibodies

Monoclonal antibodies are very useful in treating FSGS and it is designed to stop the attack to kidneys by suppressing T lymphocytes activation and over-reactive immune response. In this way, it can stop the immune inflammatory response immediately.

Blood purification

Blood purification can remove the metabolic toxins such as creatinine, urea as well as pathological antibodies in blood. It can eliminate the inducing factors of inflammatory response.

What Are the Chance of MCD Progressing into FSGS

MCD mainly occurs in children, accounting for 80% cases. It has a favorable prognosis and approximately 90% of the patients are sensitive to hormone. However, its relapse rate is as high as 60%. The patients with frequent relapse are susceptible to develop hormone-resistance or hormone-dependence. MCD can be reversed completely by early and proper treatment. Conversely, if the patients experience frequent relapses, the disease is much likely to turn into Mesangial Proliferative Glomerulonephritis and FSGS.

FSGS is a very hard condition to manage. It is reported that the patients will develop Renal Failure within 5~10 years once they are confirmed with the disease. In FSGS, a large part of glomeruli(filters) in kidneys are sclerotic and lose their normal filtering and barrier function. Thereby, a large amount of protein pass through glomeruli, ending up in urine.

So how to prevent MCD from progressing into FSGS?

If the patients with MCD are insensitive to hormone or suffer from frequent episodes, they should seek for an alternative therapy immediately to stop the disease progression.

Immunotherapy is the state-of-the-art therapy for MCD and FSGS. It treats disease aiming at enhancing or suppressing immune response. The ways of immunotherapy used in treating the disease include:

Monoclonal antibody

Monoclonal antibody can bind to and inhibit the activation of T cells to restrain over-reactive immune inflammatory response. In this way, it can rapidly stop further immune injury to kidneys.

Blood purification

Blood purification can clear up the dissociative pathological antibodies,antigens, immune complexes as well as inflammatory factors and harmful substances. Thus, it can stop them from depositing in kidneys further.

Micro-Chinese Medicine Osmotherapy

Blood purification only works for the harmful substances in blood, but the immune deposits still remain in kidneys to cause damage to kidneys. Micro-Chinese Medicine Osmotherapy can degrade the immune deposits in kidneys and make them dissolve in blood. Finally, the immune complexes will be filtered by kidneys completely. Also, it can correct immune dysregulation. By this way, the disease will be controlled from its underlying cause.

If MCD is inhibited from progressing, the patients will avoid developing FSGS completely.

Treatment for FSGS in Nephrotic Syndrome

FSGS in Nephrotic Syndrome is an difficult condition to treat. Conventionally, the patients mainly rely on hormone,immunosuppressive agents and cytoxic drugs to control blood pressure, cholesterol and heavy protein loss in urine etc. Some people will have remission after a period of treatment and return a normal life. However, it is susceptible to relapse. When they reduce hormone dosage or encounter infections, it will flare again. Besides these conventional treatments for FSGS in Nephrotic Syndrome, is there a better therapy for the condition.

FSGS is medical condition, in which the immune system attacks the kidney filtering system mistakenly.

Micro-Chinese Medicine Osmotherapy play the following roles in treating FSGS.

1. It can degrade the immune deposits in glomeruli and make them dissolve in blood. Finally, the immune deposits will be filtered out of body through systemic circulation.

2. It can regulate immune system and suppress the abnormal immune response. Hence, it can prevent the formation of immune complexes again.

3. The effective ingredients can activate the DNA replication of impaired kidney tissues and cells, thus promoting the regeneration of new renal tissues and cells. As a result, the renal function will have a remarkable improvement.
However, Micro-Chinese Medicine Osmotherapy can not eliminate the circulatory immune complexes in blood. For this part of harmful substances, blood filtration is needed to remove them out of body.


Immunotherapy can suppress the inflammatory response effectively and rapidly. Therefore, it can stop further damage to renal functional cells and tissues.



It can clear up the immune deposits in kidneys and immune complexes in blood by the combination application of Micro-Chinese Medicine Osmotherapy and blood purification techniques. Hence, it can eliminate the inducing causes of inflammatory response in kidneys.



It aims at controlling symptoms by restoring the impaired renal tissues and cells. Therefore, the patients' renal function will have a significant improvement.



It can rebuild the patients' immune system and recover the normal immune function. Hence, it can prevent immune injury to kidneys again. In this way, it stop the relapse of the disease again.

Focal Segmental Glomerulosclerosis (FSGS)

Focal Segmental Glomerulosclerosis (FSGS) is a disease that affects the kidney’s filtering system (glomeruli) causing scarring and loss of large amounts of protein in the urine. FSGS is a common cause of nephrotic syndrome.

What causes FSGS?

There is no single cause of FSGS. When the cause is not known it is called idiopathic or primary FSGS. In some patients FSGS may be the result of a genetic or inherited disease, an infection such as parvovirus or HIV/AIDS, or other kidney diseases that lead to scarring.

What are the symptoms?

Many people with FSGS have no symptoms at all. The most common complaint is edema, or swelling, especially in the legs. Often patients find that their shoes no longer fit, or that they have suddenly put on weight. High blood pressure, or hypertension, is also a very common finding. The hypertension in people with FSGS can often be very difficult to treat.

FSGS can also cause abnormal results in two different routine laboratory tests ordered by your doctor. The first is a test of kidney function called “creatinine." It is measured by taking a blood sample. Everyone has a certain amount of a substance called creatinine floating in his or her blood. This substance is always being produced by healthy muscles, but since the kidneys constantly filter it out the level of creatinine stays low. When the filters become damaged, the level of creatinine left in the blood goes up. A higher level of creatinine alerts the doctor that the kidneys aren’t filtering as well as they should.

The second test is for protein in your urine. Urine normally contains only a very small amount of protein. It is just too big to pass through the filters. But when the filters become scarred or damaged, they can “leak” protein into the urine. If a doctor finds too much protein in your urine, it usually means something is wrong with the filters. Some people with a large amount of protein in their urine say that their urine looks “foamy”, like bubbles built up in dishwater.

None of the above symptoms, or even all of them together, is specific for FSGS. If you or your doctor are concerned about FSGS, the only way to know for sure is to have a kidney biopsy.

How is FSGS diagnosed?

With information obtained from blood tests, urine tests and a kidney biopsy, a physician can determine if a person has FSGS.