Different Performances in Different Stages of Chronic Renal Insufficiency

The Chronic Renal Insufficiency is a kind of syndrome which means the kidney disease has developed into end stage. Once the functional nephrons are damaged progressively, after several months or years, the remaining nephrons can't maintain the physical environment stable, then the retention of metabolic wastes and disorder of water, electrolyte and acid-base balance will occur.

Clinically, all of chronic kidney disease can give rise to Chronic Renal Insufficiency and the most commonly seen one is Chronic Nephritis. In line with the serious degree of damaged renal function, Chronic Renal Insufficiency can be divided into four stages:

Compensatory stage: Ccr is 51～80ml/min which is higher 30% than the normal level
Decompensatory stage: Ccr is 50～20ml/min which is 25%-30% of the normal level
Renal Failure stage: Ccr is 19～10ml/min which is 20%—25% of the normal level.
Uremia stage: Ccr<10ml/min

Some people hold the idea that Chronic Renal Insufficiency is a kind of kidney disease. In fact, The Chronic Renal Insufficiency is a kind of syndrome which means the kidney disease has developed into end stage. Different degree of damaged renal function has the different symptoms and different treatments.

The compensatory stage means the early stage of kidney disease. In this period, the renal parenchyma is damaged slightly and renal function is basically normal, so the physical environment can be maintained stable and there are no obvious symptoms. In the decompensatory stage, the kidney is injured moderately and in this period, patients usually suffer from dieresis, acidosis, slight anemia and fatigues. In the Renal Failure stage, kidney has been damaged seriously and the symptoms are severer than the ones in decompensotary stage. When the disease process into Uremia, patients will present poor appetite, nausea, vomit, hypertension, even coma, insomnia, skin itching and so on.

Because there are no obvious symptoms in the early stage of Chronic Renal Insufficiency, most patients may ignore it and delay the treatment. Then the illness condition will worsen progressively. When the disease enters the stage of Uremia, patients' quality of life will decline greatly. Therefore, once we are diagnosed with Chronic Renal Insufficiency, we should take the treatment timely and positively, preventing the aggravation of the disease.